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Winning and Delivering Multi-million, Multi-year, Multi-Site, Multidisciplinary Patient Safety Research Grants
DescriptionA key driver of methodological, theoretical and substantive developments in patient safety and improved care delivery are successful multi-year collaborative multi-site grants. Using examples of two recently completed large AHRQ grants, focused on patient safety in the perioperative space, we will examine the lifecycle of these projects, the application process and grantsmanship, collaborative working between universities, hospitals and clinicians, and the implications for different grant mechanisms.

The first project was an R01 that grew out of surgeon-HF collaboration, originally following a grand rounds presentation, through a successful R03, to a fully funded R01. This focused on the challenges of integrating robotic surgery technology into the clinical environment, using flow disruptions as a primary analytic and evaluative metric. Multi-site collaboration, focused data collection, and careful management of relationships with practitioners eventually lead to a successful and innovative teamwork-related interventions. It also produced 19 publications, brought 10 individuals into healthcare HF. Ultimately, our Serious Games training method has been disturbed to about 50 organizations. This experience has subsequently led to another successful Surgeon-HF collaboration

The second was an R18 patient safety learning laboratory focused on reducing harm in anesthesia medication delivery. Conducted across two clinical sites and an engineering department, this was built on several prior collaborations and publications outside the direct area of study, but eventually lead to the identification of nearly 100 potential interventions, with 3 tested in practice and one evaluated in Virtual Reality simulation. It also generated 8 publications (so far) and introduced 8 people to healthcare HF.

Exploring the R01 and R18 Learning Laboratory allows a direct comparison between two markedly different grant mechanisms, and how these two different approaches lead to different processes and outcomes. More generally, it provides the audience with an opportunity to learn about the lifecycle of major healthcare research projects, providing a wider view of both the substantive findings, and the processes that underlie successful research.

Overview of the Projects (Ken Catchpole)
Ken was PI on both projects. He will give an overview of how they came about, the course that each one took, and outline the findings and publications, including:
• Recognizing the opportunity - what AHRQ is looking for.
• Writing the grant - timelines, challenges, budgets.
• Identifying your team – How the working relationships came about and developed.
• Gestation of the research ideas from pre-grant, through the project, to the next steps.
• What does this do for knowledge in HF and patient safety.
• Why working in this way is important

Proposing and Running a Grant in the Real World (Tara Cohen)
Tara was a PI on the HF-SIgHTS R01 grant and is now also a successful PI for a new R18 Patient Safety Learning Laboratory. She will discuss the challenges of applying for and running a grant of this size, length, and complexity, including:
• Challenges with running multi-site projects. Different IRBS, Different processes / org leadership, interventions are not universally accepted.
• Managing the unexpected/being flexible. Staffing changes (e.g., burnout, disinterest in project)/ departmental rules (no surveys) / grant rules (e.g., no funding for food/ participation awards
• Running these projects during COVID-19
• Key results from the grant.
• Building on this experience with future projects and grants.
Anesthesiologist’s Perspective (Jake Abernathy)
Jake was Co-PI and clinical lead for the R18 Learning Lab. His research interest has been in HF for many years. He will describe
• Working with HF professionals
• Motivation and interest
• Developing local collaboration and support
• Challenges & Successes.
• Perspective on HF for clincal use, as clinical research.
Surgeon’s Perspective (Jennifer Anger)
Jennifer was Co-PI and clinical lead for the R01 grant. She already had a strong publication record and interest in health services research but was relatively new to HF when we began to collaborate.
• Working with HF professionals
• Motivation and interest
• Developing local collaboration and support
• Challenges & Successes.
• Perspective on HF for clinical use, as clinical research.
• Building on this work for a new Patient Safety Learning Laboratory.
Engineer’s Perspective (David Neyens)
Dave was Co-PI on the R18 Learning Laboratory. With a long-standing interest in HF across multiple domains, he had prior experience with an earlier Learning Laboratory. He will discuss:
• Motivation and interest in the collaboration
• Support in an Engineering School
• How to get the work done remotely
• Challenges & Successes
• Key results of the grant.
• Perspective on Healthcare HF from ‘afar’.
Event Type
Discussion Panel
TimeTuesday, March 263:30pm - 4:30pm CDT
LocationSalon A-3
Tracks
Patient Safety Research and Initiatives